## Abstract Using tissue engineering, a complex of neural stem cells (NSCs) and collagen type I was transplanted for the therapy of cerebral ischemic injury. NSCs from E14 d rats were dissociated and cultured by neurosphere formation in serum‐free medium in the presence of basic fibroblast growth f
✦ LIBER ✦
Transplantation of neural stem cells modified by human neurotrophin-3 promotes functional recovery after transient focal cerebral ischemia in rats
✍ Scribed by Zi-heng Zhang; Ren-zhi Wang; Ren-zhi Wang; Gui-lin Li; Jun-ji Wei; Zhao-jian Li; Ming Feng; Jun Kang; Wan-chen Du; Wen-bin Ma; Yong-ning Li; Yi Yang; Yan-guo Kong
- Book ID
- 116770779
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 415 KB
- Volume
- 444
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Previous studies have suggested that intravenous transplantation of mesenchymal stem cells (MSCs) in rat ischemia models reduces ischemia‐induced brain damage. Here, we analyzed the expression of neurotrophic factors in transplanted human MSCs and host brain tissue in rat middle cerebra