Transplantation of Mesenchymal Stem Cells Promotes an Alternative Pathway of Macrophage Activation and Functional Recovery after Spinal Cord Injury
β Scribed by Nakajima, Hideaki; Uchida, Kenzo; Guerrero, Alexander Rodriguez; Watanabe, Shuji; Sugita, Daisuke; Takeura, Naoto; Yoshida, Ai; Long, Guang; Wright, Karina T.; Johnson, William E.B.; Baba, Hisatoshi
- Book ID
- 119994046
- Publisher
- Mary Ann Liebert
- Year
- 2012
- Tongue
- English
- Weight
- 665 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0897-7151
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Transplantation of neural stem cells (NSCs) has shown promise for improving functional recovery after spinal cord injury (SCI). The inhospitable milieu of injured spinal cord, however, does not support survival of grafted NSCs, reducing therapeutic efficacy of transplantation. The present study soug
## Abstract We compared the neurological and electrophysiological outcome, glial reactivity, and spared spinal cord connectivity promoted by acute transplantation of olfactory ensheathing cells (group OEC) or Schwann cells (group SC) after a mild injury to the rat spinal cord. Animals were subjecte