I n 1947 vvhilme routinely autopsying rats a t the Xational Cancer Institute in Bethesda, Maryland, I found an animal which had one kidney missing. This was an inbred black agouti rat from strain AXC9935 (commonly referred to as "Irish"). During the course of succeediiig autopsies, I observed a sig-
Transplantation of chemically induced adenocarcinomas of the colon in an inbred strain of rats
β Scribed by Dolly Cannamela McCall; Jack W. Cole
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 926 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
Adenocarcinomas of the colon were chemically induced with 1,Z-dimethylhydrazine in 6 of 10 inbred Buffalo strain m a l e rats. The tumor has been successfully transplanted by intraperitoneal and/or subcutaneous inoculations through five successive passages with preservation of the original histologic appearance.
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