Recent studies have shown that delayed transplantation of neural stem/progenitor cells (NSPCs) into the injured spinal cord can promote functional recovery in adult rats. Preclinical studies using nonhuman primates, however, are necessary before NSPCs can be used in clinical trials to treat human pa
Transplantation of a combination of autologous neural differentiated and undifferentiated mesenchymal stem cells into injured spinal cord of rats
β Scribed by Pedram, M S; Dehghan, M M; Soleimani, M; Sharifi, D; Marjanmehr, S H; Nasiri, Z
- Book ID
- 109976725
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 513 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1362-4393
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Early and robust invasion by macrophages may be one of the reasons why axonal regeneration is more effective in the PNS than in the CNS. Therefore, we have grafted autologous peritoneal macrophages labeled with fluorescent latex microspheres into spinal cord compression lesions. At various survival
## Abstract Adult mesenchymal stem cells (MSCs) exhibit neuroprotective properties when introduced into the degenerating central nervous system through different putative mechanisms including secretion of growth factors and transdifferentiation. In the present study, we injected MSCs into the cereb