Transplantability of Mammary Gland in Brown Fat Pads of Mice
β Scribed by HOSHINO, KAZUMASA
- Book ID
- 109655073
- Publisher
- Nature Publishing Group
- Year
- 1967
- Tongue
- English
- Weight
- 470 KB
- Volume
- 213
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/213194a0
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Normal human breast tissue was enzymatically dissociated and the cells were injected into the gland-free fat-pads of athymic nude mice. Within 30 days, small, spherical, duct-like epithelial elements (organoids) formed in 68% of the fat-pads inoculated (0-23 organoidslfat-pad). Short-term (30-day) t
The culturing of lung tissues in diffusion chambers in vivo has failed to support epithelial elements. The transplantation of lung rudiments into mammary fat pads of mice, however, has allowed long term culture (11 months)