## Abstract Immune mechanisms involved in control of cytomegalovirus (CMV) infection in the allogeneic stem cell transplantation setting have not been fully disclosed. CMV pp65 and IE‐1‐specific CD8^+^ T cells expressing IFN‐γ, TNF‐α, and CD107a, alone or in combination, and NKG2C^+^ NK cells were
✦ LIBER ✦
Transplant conditions determine the kinetics and frequency of homeostatically expanding memory CD8 T cells in syngeneic HCT recipients
✍ Scribed by M. Roskos; R.B. Levy
- Book ID
- 116278698
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 66 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1083-8791
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## Abstract The dynamics of CMV pp65 and IE‐1‐specific IFNγ‐producing CD8^+^ (IFNγ CD8^+^) and CD4^+^ (IFNγ CD4^+^) T cells and CMV DNAemia were assessed in 19 pre‐emptively treated episodes of active CMV infection. Peripheral counts of IFNγ CD8^+^ and IFNγ CD4^+^ T cells inversely correlated with