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Transplacental exposure to antipsychotic drugs during pregnancy and megacystis in the fetus

✍ Scribed by Suzuka Okuno; Hiromi Hamada; Yutaka Fujiki; Mana Yasuoka; Hideki Watanabe; Naoki Yamada; Satoshi Sohda; Takeshi Kubo

Book ID: 101236242
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 174 KB
Volume: 19
Category: Article
ISSN: 0197-3851
DOI: 10.1002/(sici)1097-0223(199910)19:10<980::aid-pd669>3.0.co;2-3

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✦ Synopsis

Urinary retention is an adverse effect of antipsychotic drugs that has not been previously reported in the fetus. We have diagnosed megacystis in a fetus possibly caused by transplacental exposure to the antipsychotic drugs being administered to the mother. Two weeks after the mother stopped taking the drugs, the size of the enlarged fetal urinary bladder returned to normal. Sonographic examination of the neonate revealed an anatomically normal urinary tract, with a normal bladder capacity and urination.

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