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Transmucosal transport of tobramycin incorporated in solid lipid nanoparticles (sln) after duodenal administration to rats. Part II—Tissue distribution

✍ Scribed by Alessandro Bargoni; Roberta Cavalli; Gian Paolo Zara; Anna Fundarò; Otto Caputo; Maria Rosa Gasco


Book ID
118770968
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
83 KB
Volume
43
Category
Article
ISSN
1043-6618

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✍ Zara, Gian Paolo (author);Bargoni, Alessandro (author);Cavalli, Roberta (author) 📂 Article 📅 2002 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 143 KB

Idarubicin-loaded solid lipid nanoparticles (IDA-SLN) and idarubicin in solution were prepared and the two formulations were administered to rats, either by the duodenal route or intravenously (iv). The aim of this research was to study whether the bioavailability of idarubicin can be improved by ad