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Transmission of mitochondrial DNA disorders: possibilities for the future

✍ Scribed by DT Brown; M Herbert; VK Lamb; PF Chinnery; RW Taylor; RN Lightowlers; L Craven; L Cree; JL Gardner; DM Turnbull

Book ID
117299503
Publisher
The Lancet
Year
2006
Tongue
English
Weight
62 KB
Volume
368
Category
Article
ISSN
0140-6736

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✍ J. Poulton; D. R. Marchington πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 905 KB

Mitochondria have their own DNA which is maternally inherited. Mitochondria1 DNA (mtDNA) diseases are extremely variable because of the genetics of mtDNA and the unique pathogenesis of these disorders. This makes predicting the prognosis and the transmission of mtDNA disorders difficult. While mtDN