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Transmissible subacute spongiform encephalopathies

✍ Scribed by D. Dormont

Book ID
117576301
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
155 KB
Volume
53
Category
Article
ISSN
0753-3322

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Theoretical Analysis of the Implication
Theoretical Analysis of the Implication of PrP in Neuronal Death during Transmissible Subacute Spongiform Encephalopathies: Hypothesis of a PrP Oligomeric Channel
✍ YVES CHAPRON; JEAN-MICHEL PEYRIN; SERGE CROUZY; ALEXANDRE JAEGLY; DOMINIQUE DORM πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 580 KB

Transmissible subacute spongiform encephalopathies (TSE) are animal and human neurodegenerative diseases. The nature of the transmissible agent remains unknown. The speci"c molecular marker of these diseases is the abnormal isoform of the prion protein (PrP). This protein is encoded by a cellular ge