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Transmembrane passage of hydrophobic compounds through a protein channel wall

✍ Scribed by Hearn, Elizabeth M.; Patel, Dimki R.; Lepore, Bryan W.; Indic, Mridhu; van den Berg, Bert


Book ID
109897967
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
643 KB
Volume
458
Category
Article
ISSN
0028-0836

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## Abstract __Regular phospholipid bilayers do not pose efficient barriers for the transport of hydrophobic molecules. The outer membrane (OM) surrounding Gram‐negative bacteria is a nontypical, asymmetric bilayer with an outer layer of lipopolysaccharide (LPS). The sugar molecules of the LPS layer