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Transmembrane helix dimerization: Beyond the search for sequence motifs

✍ Scribed by Edwin Li; William C. Wimley; Kalina Hristova


Book ID
116275230
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
692 KB
Volume
1818
Category
Article
ISSN
0005-2736

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A more global search method, using fewer assumptions, has been used to predict the structure of the dimeric transmembrane region of the protein glycophorin A. The resulting model significantly differs from that previously determined. In particular, the arrangement between the two transmembrane helic