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Translocation of a supernumerary Y to a 15: Study of six cases (three males and three females) in three generations

โœ Scribed by J. Benitez; L. Rivera; C. Ramos; E. Tejedor; A. Sanchez-Cascos


Publisher
Springer
Year
1979
Tongue
English
Weight
280 KB
Volume
48
Category
Article
ISSN
0340-6717

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โœฆ Synopsis


We present a family in which six members (three males and three females) carry a translocation of the fluorescent part of a supernumerary Y to a 15. The carriers do not have any impairment of fertility or any malformation.


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## Abstract The __Aristaless__ Related Homeobox (__ARX__) gene is a Q~50~ paired homeobox gene. These genes are important regulators of essential events during vertebrate embryogenesis, including the development of the central and peripheral nervous system. Mutations in __ARX__ have been identified