Translocation 4p;21q identified by FISH in a case previously described as “presumptive monosomy 21”

A case of presumptive monosomy 21 re-dia

A case of presumptive monosomy 21 re-diagnosed as unbalanced t(5p;21q) by FISH and review of literature

✍ Iqbal, M. Anwar; Ahmed, Mohammed Zein Seid; Wu, David; Sakati, Nadia 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 1 views

By using fluorescence in situ hybridization (FISH), we demonstrate a case of monosomy 21 to result from an unbalanced translocation involving the short arm of chromosome 5 and the long arm of chromosome 21. Our case is compared to 3 similar cases of t(5p;21q) reported recently, which were also origi