Translocation (1;22)(p36;q11.2) with concurrent del(22)(q11.2) resulted in homozygous deletion ofSNF5/INI1in a newly established cell line derived from extrarenal rhabdoid tumor

Cytogenetic and molecular analysis of a

Cytogenetic and molecular analysis of a t(1;22)(p36;q11.2) in a rhabdoid tumor with a putative homozygous deletion of chromosome 22

✍ Christophe Rosty; Martine Peter; Jessica Zucman; Pierre Validire; Olivier Delatt 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 2 views

Malignant rhabdoid tumors are rare and aggressive neoplasms of childhood, occurring in the kidney or in various extrarenal locations. Most cytogenetic studies of these tumors have shown the frequent involvement of chromosome 22, including translocations and/or deletions, with a critical region for a