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Translational potential of naloxone and naltrexone as TLR4 antagonists

โœ Scribed by Skolnick, Phil; Davis, Hirsch; Arnelle, Derrick; Deaver, Daniel

Book ID
126776304
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
306 KB
Volume
35
Category
Article
ISSN
0165-6147

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A comparison of naloxone and naltrexone
A comparison of naloxone and naltrexone in laboratory tests predictive of antipsychotic potential
โœ Dr. Jeffrey B. Malick; Raymond L. Herman; Jeffrey M. Goldstein ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 514 KB

Naloxone and naltrexone were compared neuropharmacologically, especially in several rodent models considered to be predictive of antipsychotic activity, since narcotic antagonists have been reported to be effective in the treatment of schizophrenia. Naltrexone was found to be a potent antagonist of