✦ LIBER ✦

Translation of human immunoglobulin heavy chain mRNA in vitro

✍ Scribed by KLUKAS, CAROL K.; CRAMER, FRANS; GOULD, HANNAH

Book ID: 109707104
Publisher: Nature Publishing Group
Year: 1977
Tongue: English
Weight: 421 KB
Volume: 269
Category: Article
ISSN: 0028-0836
DOI: 10.1038/269262a0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Immunoglobulin heavy chain mRNA in mitog

Immunoglobulin heavy chain mRNA in mitogen-stimulate B cells

✍ R. H. Stevens; Brigitte A. Askonas; Jacqueline L. Welstead 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 778 KB

## Abstract This paper relates the synthesis of DNA, immunoglobulin and heavy chain (H) MRNA in murine spleen cells following activation of B cells with lipopolysaccharide from __E. Coli__ (LPS). Spleen cells (CBA/H mice) were cultivated with 10 % FCS and 10 μg LPS/ml. 4 h pulses with [^3^H]thymid

Co-translational modification of nascent

Co-translational modification of nascent immunoglobulin heavy and light chains

✍ Bergman, Lawrence W. ;Kuehl, W. Michael 📂 Article 📅 1979 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 1002 KB

## Abstract We have investigated the in vivo co‐translational covalent modification of nascent immunoglobulin heavy and light chains. Nascent polypeptides were separated from completed polypeptides by ion‐exchange chromatography of solubilized ribosomes on QAE‐Sephadex. First, we have demonstrated

VHD rearrangements in human immunoglobul

VHD rearrangements in human immunoglobulin heavy chain minilocus transgenic mice

✍ Nadine Tuaillon; J. Donald Capra 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB

Typically, immunoglobulin VHDJH recombination is performed in two steps with D to JH rearrangement preceding VH to DJH rearrangement. Using a human immunoglobulin heavy chain transgenic minilocus, we previously demonstrated that a non-conventional human D gene segment termed DIR2 could be recombined

Polymorphism of heavy chain immunoglobul

Polymorphism of heavy chain immunoglobulin isotypes in theMussubgenus

✍ Mounira Amor; Francois Bonhomme; Jean-Louis Guenet; Francis Petter; Pierre-André 📂 Article 📅 1984 🏛 Springer-Verlag 🌐 English ⚖ 248 KB

The role of immunoglobulin heavy chain b

The role of immunoglobulin heavy chain binding protein: in immunoglobulin transport

✍ Linda Hendershot; David Bole; John F. Kearney 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 545 KB

C-terminal lysine processing of human im

C-terminal lysine processing of human immunoglobulin G2 heavy chain in vivo

✍ Bing Cai; Hai Pan; Gregory C. Flynn 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 361 KB

## Abstract Although human IgG heavy chain genes encode a C‐terminal lysine, this residue is mostly absent from the endogenous antibodies isolated from serum. Some low but variable level of C‐terminal lysine is present on therapeutic antibodies expressed in mammalian cell culture systems. Here, we