Translating Tumor Antigens into Cancer Vaccines
โ Scribed by Buonaguro, L.; Petrizzo, A.; Tornesello, M. L.; Buonaguro, F. M.
- Book ID
- 111904747
- Publisher
- American Society for Microbiology
- Year
- 2010
- Tongue
- English
- Weight
- 968 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1556-6811
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Tumor antigens recognized by human cytotoxic T lymphocytes (CTL) have been identified for multiple types of solid tumors. These include both shared and unique antigens. Unique antigens are those expressed uniquely by one patient's tumor, and shared antigens are those present on tumor cells from many
Tumor vaccinology is as old as immunological thought and as young as our rapidly evolving understanding of antigen processing and presentation. The recent availability of carbohydrate and peptide tumor antigens suitable for vaccine construction, conjugate and recombinant vector technologies capable