Transition Temperature and Heat of Crystallization of Amorphous Bulk Gallium Antimonide Obtained by Rapid Quenching from the Melt at High Pressure

Explanation of the crystallization rate

Explanation of the crystallization rate of amorphous nifedipine and phenobarbital from their molecular mobility as measured by 13C nuclear magnetic resonance relaxation time and the relaxation time obtained from the heating rate dependence of the glass transition temperature

✍ Yukio Aso; Sumie Yoshioka; Shigeo Kojima 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

To gain further insight into the effect of molecular mobility on the crystallization rate of amorphous drugs, the mean relaxation times of amorphous nifedipine and phenobarbital were calculated based on the Adam±Gibbs±Vogel (AGV) equation, using the parameters D, T 0 , and T f , derived from the hea