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Transition-metal-catalyzed reactions of trimethylsilyl cyanide. 4. Palladium-catalyzed cyanation of aryl halides by trimethylsilyl cyanide

โœ Scribed by Chatani, Naoto; Hanafusa, Terukiyo


Book ID
111937123
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
445 KB
Volume
51
Category
Article
ISSN
0022-3263

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We examined the palladium-catalyzed cyanation of hindered, electron-rich aryl triflates by zinc cyanide using 2-methoxyphenyl trifluoromethanesulfonate (4) as a model compound. The reaction with two equivalents of Zn(CN) 2 and catalytic Pd(PPh3) 4 in DMF at 120ยฐC for 2 hr affonJed 2-methoxybenzonitr