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Transient structural change in hepatic DNA of rats chronically exposed to dimethylnitrosamine

โœ Scribed by Kosic, Jugana; Stewari, Bernard W.

Book ID
121999710
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
551 KB
Volume
20
Category
Article
ISSN
0304-3835

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The chronic dietary administration of hexachlorobenzene (HCB) to rats for a year or more results in the formation of liver tumours described as hepatocellular carcinomas, hepatomas or haemangiomas. The hepatotoxicity of HCB, which is greatest in hamsters and rats, gives rise to peliosis and necrosis