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Transient Permeability Leak of Nuclear Envelope Induced by Aldosterone

โœ Scribed by I. Buchholz; K. Enss; C. Schafer; A. Schlune; V. Shahin; H. Oberleithner


Book ID
105926322
Publisher
Springer
Year
2004
Tongue
English
Weight
217 KB
Volume
199
Category
Article
ISSN
0022-2631

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Nuclear envelope barrier leak induced by
โœ Lilian Kastrup; Hans Oberleithner; Yvonne Ludwig; Claudia Schafer; Victor Shahin ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 377 KB

## Abstract Nuclear pore complexes (NPCs) are multiprotein channels that span the nuclear envelope. They strongly limit the efficiency of gene transfection by restriction of nuclear delivery of exogenously applied therapeutic macromolecules. NPC dilation could significantly increase this efficiency