Transient Notch signaling induces NK cell potential in Pax5-deficient pro-B cells

Rapid in vivo analysis of mutant forms o

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells

✍ Laurence Ardouin; Antonius G. Rolink; Anne-Marie Mura; Julien Gommeaux; Fritz Me 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB

## Abstract Following injection into recombinase‐activating gene‐deficient (__Rag1__^–/–^) mice, pro‐B cells lacking the Pax5 transcription factor (__Pax5__^–/–^) develop into most major hematopoietic lineages, with the notable exception of B cells. We assessed whether __Pax5__^–/–^ pro‐B cells tha