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Transient Hyperammonemia Due to Urea Cycle Enzyme Deficiency in Irish Wolfhounds

โœ Scribed by M.M.J.M. Zandvliet; J. Rothuizen


Book ID
118094657
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
161 KB
Volume
21
Category
Article
ISSN
0891-6640

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Ammonia liberated during amino acid catabolism in mammals is highly neurotoxic and is detoxified by the five enzymes of the urea cycle that are expressed within the liver. Inborn errors of each of the urea cycle enzymes occur in humans. Carbamoyl phosphate synthetase I (CPSase I; EC 6.3.4.16) is loc