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Transient expression and flux changes during a shift from high to low riboflavin production in continuous cultures of Bacillus subtilis

โœ Scribed by Nicola Zamboni; Eliane Fischer; Andrea Muffler; Markus Wyss; Hans-Peter Hohmann; Uwe Sauer


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
280 KB
Volume
89
Category
Article
ISSN
0006-3592

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Transient expression and flux changes du
โœ Nicola Zamboni; Eliane Fischer; Andrea Muffler; Markus Wyss; Hans-Peter Hohmann; ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 280 KB ๐Ÿ‘ 1 views

At the onset of glucose-limited continuous cultures, riboflavin production in recombinant Bacillus subtilis declines significantly within 3 generations. This phenomenon was specific to riboflavin production and was not correlated with any other physiological parameter. Physiological analyses exclude