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Transient Depletion of Dividing T Lymphocytes in Mice Induces the Emergence of Regulatory T Cells and Dominant Tolerance to Islet Allografts

✍ Scribed by S. Giraud; B. Barrou; S. Sebillaud; P. Debré; D. Klatzmann; V. Thomas-Vaslin


Book ID
114804719
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
555 KB
Volume
8
Category
Article
ISSN
1600-6135

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Posttransplant total lymphoid irradiation is a nonmyeloablative regimen that has been extensively studied in rodent models for the induction of tolerance to bone marrow and solid organ allografts. Previous studies of experimental models and clinical transplantation have used total lymphoid irradiati