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Transient cerebral ischemia increases CA1 pyramidal neuron excitability

✍ Scribed by Yuan Fan; Ping Deng; Yu-Chi Wang; Hui-Chen Lu; Zao C. Xu; Paul E. Schulz

Book ID
116459356
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
919 KB
Volume
212
Category
Article
ISSN
0014-4886

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## Abstract In the presence of spiperone to block the 5‐HT~1A~‐mediated inhibition of pyramidal cell activity, 5‐hydroxytryptamine (serotonin, 5‐HT) produces a rapid transient increase in amplitude of the extracellularly recorded population spike from area CA1 of the hippocampus. Intracellular reco