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Transient and Selective Overexpression of Dopamine D2 Receptors in the Striatum Causes Persistent Abnormalities in Prefrontal Cortex Functioning

✍ Scribed by Christoph Kellendonk; Eleanor H. Simpson; H. Jonathan Polan; Gaël Malleret; Svetlana Vronskaya; Vanessa Winiger; Holly Moore; Eric R. Kandel


Book ID
116782591
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
556 KB
Volume
49
Category
Article
ISSN
0896-6273

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✍ Gurevich, Eugenia V.; Joyce, Jeffrey N. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 788 KB

The rodent primary somatosensory cortex (SI) contains a map of the body surface, the most conspicuous part of which are "barrels," neuronal aggregates in layer IV that receive somatotopic projections from whiskers on the rodent's snout. We report that the D 3 dopamine receptor (D 3 R) is selectively