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Transgenic Overexpression of Granulocyte Macrophage-Colony Stimulating Factor in the Lung Prevents Hyperoxic Lung Injury

✍ Scribed by Robert Paine III; Steven E. Wilcoxen; Susan B. Morris; Claudio Sartori; Carlos E.O. Baleeiro; Michael A. Matthay; Paul J. Christensen


Book ID
117021749
Publisher
American Society for Investigative Pathology
Year
2003
Tongue
English
Weight
488 KB
Volume
163
Category
Article
ISSN
0002-9440

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## Abstract We previously established 2 lung cancer cell lines, OKa‐C‐1 and MI‐4, which constitutively produce an abundant dose of granulocyte‐colony stimulating factor (G‐CSF) and granulocyte macrophage‐colony stimulating factor (GM‐CSF). Many other cases with G‐CSF or GM‐CSF producing tumors have