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Transgenic mice expressing the human low density lipoprotein receptor: A new approach to study protein sorting in the hepatocyte

✍ Scribed by Yokode, M.


Book ID
123086308
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
100 KB
Volume
1
Category
Article
ISSN
0928-4680

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Using DNA sequencing of the coding and exon flanking regions of the low density lipoprotein receptor (LDLR) gene we identified an Alw26 I site in exon 10 by a transition G1426A. The alleles are represented by one uncut fragment (A1 = 108 bp) or two fragments (A2 = 82bp and 26 pb). Two other fragment