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Transgenic Expression of FGF8 and FGF10 Induces Transdifferentiation of Pancreatic Islet Cells into Hepatocytes and Exocrine Cells

โœ Scribed by Takashi Yamaoka; Kenji Yoshino; Taketo Yamada; Makiko Yano; Takefumi Matsui; Takashi Yamaguchi; Maki Moritani; Jun-ichi Hata; Sumihare Noji; Mitsuo Itakura

Book ID
115589648
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
400 KB
Volume
292
Category
Article
ISSN
0006-291X

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Pancreatic islets are enveloped by a sheath of Schwann cells, the glial cells of the peripheral nervous system (PNS). The fact that Schwann cells of the PNS become reactive and express nerve growth factor (NGF) and other growth factors following axotomy suggested the possibility that peri-islet Schw