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Transgenic Animal Models for Type 1 Diabetes: Linking a Tetracycline-Inducible Promoter with a Virus-Inducible Mouse Model

โœ Scribed by Urs Christen; Matthias G. von Herrath

Book ID
110404323
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
186 KB
Volume
11
Category
Article
ISSN
0962-8819

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โœ Akari Inada; Hiroshi Kanamori; Hidenori Arai; Tomoyuki Akashi; Makoto Araki; Gor ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 651 KB

## Abstract We have previously found progressive diabetic nephropathy in inducible cAMP early repressor (ICER Iฮณ) transgenic (Tg) mice. The ICER Iฮณ Tg mouse is an interesting model of sustained hyperglycemia due to its low production of insulin and insulinโ€producing ฮฒ cells. Here in a longitudinal