Pathogenesis of CADASIL : Transgenic and
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Anne Joutel
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Article
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2010
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John Wiley and Sons
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English
โ 491 KB
## Abstract Small vessel diseases (SVDs) of the brain are the leading cause of vascular cognitive impairment and a major contributor to stroke in the human adult, however, their pathogenesis is poorly understood. Dominant mutations in __NOTCH3__ cause CADASIL, one of the most prevalent inherited ce