## Abstract The small G protein Ras, which is involved critically in neurotrophic signal transduction, has been implicated in neuronal plasticity of both the developing and the adult nervous systems. In the present study, the cumulative effects of constitutive Ras activity from early in postnatal d
✦ LIBER ✦
Transgenic Activation of Ras in Neurons Promotes Hypertrophy and Protects from Lesion-induced Degeneration
✍ Scribed by Heumann, R.
- Book ID
- 126874991
- Publisher
- Rockefeller University Press.
- Year
- 2000
- Tongue
- English
- Weight
- 589 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0021-9525
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## Abstract We have previously shown that intrastriatal injection of ΔRR, the growth‐compromised herpes simplex virus type 2 (HSV‐2) vector for the antiapoptotic protein ICP10PK, prevents apoptosis caused by the excitotoxin N‐methyl‐D‐aspartate (NMDA) in a mouse model of glutamatergic neuronal cell