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Transfusion in the Patient With Sickle Cell Disease: A Critical Review of the Literature and Transfusion Guidelines

โœ Scribed by Cassandra D. Josephson; Leon L. Su; Krista L. Hillyer; Christopher D. Hillyer


Book ID
113933379
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
178 KB
Volume
21
Category
Article
ISSN
1532-9496

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## Abstract Patients with sickle cell disease (SCD) appear to be at lower risk of endocrinopathies and cardiac dysfunction than those with thalassemia major (TM). Circulating redox active iron is lower in these patients, possibly due to increased systemic inflammation and circulating cytokines. Hep