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Transforming Growth Factor-β2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling

✍ Scribed by van't Land, B; Meijer, H P; Frerichs, J; Koetsier, M; Jager, D; Smeets, R L; M'Rabet, L; Hoijer, M

Book ID
109997275
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
120 KB
Volume
87
Category
Article
ISSN
0007-0920

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Damage to the normal replacing tissues of the body, specifically the gastro-intestinal tract, limits the treatment and hence, cure rate of cancer patients. Here, we investigate the possibility that the sensitivity of the gastro-intestinal tract can be manipulated by transforming growth factor beta3