Transforming growth factor-β1 regulates SR function of cultured rat cardiomyocytes
✍ Scribed by Simon M Bryant; Craig B Neylon; Alex Bobik
- Book ID
- 115985476
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 114 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0022-2828
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A complex interrelationship exists between the extracellular matrix and cytokine signaling in articular chondrocytes. We sought to determine whether the extracellular matrix serves as a regulatory component of transforming growth factor-beta1 expression. Bovine articular chondrocytes were isolated a
## ABSTRACT Transforming growth factor β1 (TGFβ1) elevated the phosphoenolpyruvate carboxykinase (PEPCK) mRNA abundance in primary cultures of rat hepatocytes. Although this increase was not as large as the rise in PEPCK gene expression induced by the cAMP‐elevating agents glucagon or isoproterenol