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Transforming growth factor-β1 induces extracellular matrix formation in glomerulonephritis

✍ Scribed by Wayne A. Border; Erkki Ruoslahti


Book ID
113395943
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
534 KB
Volume
32
Category
Article
ISSN
0922-3371

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✍ Gouri Shanker; Dan Olson; Roger Bone; Rajinder Sawhney 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 372 KB

Transforming growth factor beta-1 (TGF-1 ), which is present in lung tissue, has been suggested to play a role in modulating vascular cell function in vivo. The action of TGF-1 in vivo, especially at the local site of application to connective tissue, is anabolic and leads to pulmonary fibrosis and