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Transforming growth factor-β1 gene polymorphism modifies the histological and clinical manifestations in Japanese patients with IgA nephropathy

✍ Scribed by F. Sato; I. Narita; S. Goto; D. Kondo; N. Saito; J. Ajiro; D. Saga; A. Ogawa; M. Kadomura; F. Akiyama; Y. Kaneko; M. Ueno; M. Sakatsume; F. Gejyo

Book ID
110892002
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
162 KB
Volume
64
Category
Article
ISSN
0001-2815

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✍ T. Ohtsuka; A. Yamakage; S. Yamazaki 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB

## Background: Transforming growth factor (tgf)-beta has been shown to be a potent stimulator of collagen production by fibroblasts, and could play a role in the pathogenesis of systemic sclerosis (ssc). ## Objective: To study the possible involvement of tgf-beta1 gene polymorphism in japanese pa