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Transforming growth factor β stimulates rheumatoid synovial fibroblasts via the type II receptor

✍ Scribed by Yanjmaa Bira; Kenji Tani; Yasuhiko Nishioka; Junya Miyata; Keiko Sato; Akihito Hayashi; Yutaka Nakaya; Saburo Sone


Book ID
106291735
Publisher
Springer
Year
2005
Tongue
English
Weight
262 KB
Volume
15
Category
Article
ISSN
1439-7595

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## Abstract ## Objective Aberrant transforming growth factor β (TGFβ) signaling has been implicated in the pathogenesis of scleroderma (systemic sclerosis [SSc]), but the contribution of specific components in this pathway to SSc fibroblast phenotype remains unclear. This study was undertaken to d