Enhanced tumorigenesis and reduced trans
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Yang Kang; Jennifer M. Mariano; Jerry Angdisen; Terry W. Moody; Bhalchandra A. D
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Article
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2000
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John Wiley and Sons
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English
⚖ 306 KB
👁 1 views
To elucidate the role of transforming growth factor-beta1 (TGF-beta1) and the TGF-beta type II receptor (TGF-beta RII) as tumor-suppressor genes in lung carcinogenesis, we mated C57BL/6 mice heterozygous (HT) for deletion of the TGF-beta1 gene with A/J mice to produce AJBL6 TGF-beta1 HT progeny and