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Transforming growth factor β mediates increase of mature transmembrane amyloid precursor protein in microglial cells

✍ Scribed by Ursula Mönning; Rupert Sandbrink; Richard B. Banati; Colin L. Masters; Konrad Beyreuther


Book ID
115930296
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
855 KB
Volume
342
Category
Article
ISSN
0014-5793

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## Abstract Insulin‐like growth factor binding protein‐3 (IGFBP‐3) has been proposed to mediate the growth inhibitory effects of transforming growth factor (TGF)‐β in breast and prostate cancer cells. Both TGF‐β and exogenous IGFBP‐3 inhibit DNA synthesis in Mv1 mink lung epithelial cells (CCL64).