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Transforming growth factor β inhibits steroidogenic acute regulatory (StAR) protein expression in human ovarian thecal cells

✍ Scribed by George R Attia; Christina A Dooley; William E Rainey; Bruce R Carr

Book ID
117462536
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
708 KB
Volume
170
Category
Article
ISSN
0303-7207

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## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited