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Transforming growth factor β inhibitory element in the rabbit matrix metalloproteinase-1 (collagenase-1) gene functions as a repressor of constitutive transcription

✍ Scribed by Lori A. White; Teresa I. Mitchell; Constance E. Brinckerhoff


Book ID
114147023
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
343 KB
Volume
1490
Category
Article
ISSN
0167-4781

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Transforming growth factor-b (TGF-b) increases steady-state mRNA levels of several extracellular matrix proteins in mineralized connective tissues. Bone sialoprotein (BSP) is a major constituent of the bone matrix, thought to initiate and regulate the formation of mineral crystals. To determine the