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Transforming growth factor-β, but not ciliary neurotrophic factor, inhibits DNA synthesis of adrenal medullary cells in vitro

✍ Scribed by N Wolf; K Krohn; S Bieger; M Frödin; S Gammeltoft; K Krieglstein; K Unsicker

Book ID
117492703
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
419 KB
Volume
90
Category
Article
ISSN
0306-4522

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✍ Feng Dong; Hai-Bin WU; Jiang Hong; Matthew M. Rechler 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 2 views

## Abstract Insulin‐like growth factor binding protein‐3 (IGFBP‐3) has been proposed to mediate the growth inhibitory effects of transforming growth factor (TGF)‐β in breast and prostate cancer cells. Both TGF‐β and exogenous IGFBP‐3 inhibit DNA synthesis in Mv1 mink lung epithelial cells (CCL64).