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Transforming growth factor β and activin tonically inhibit DNA synthesis in the rat liver

✍ Scribed by Takeshi Ichikawa; You-Qing Zhang; Kimitaka Kogure; Yoshihisa Hasegawa; Hitoshi Takagi; Masatomo Mori; Itaru Kojima

Book ID
111721656
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
296 KB
Volume
34
Category
Article
ISSN
0270-9139

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Transforming growth factor β 1 (TGF-β 1 ) has been implicated as inhibitor of cell proliferation and a potent inducer of apoptosis in vitro and in vivo after the administration of high doses. To assess the role of endogenous TGF-β 1 , we quantitated the cytokine and its receptors in rat liver during