In the human glioblastoma cell line, T-MG1, plasminogen activator activity (PA-activity) was demonstrated by using the chromogenic substrate S-2251. Using monoclonal antibodies against human urokinase type PA (u-PA) and human tissue type PA (t-PA), only u-PA activity was found in T-MG1 cell extracts
✦ LIBER ✦
Transforming growth factor β alters plasminogen activator activity in human skin fibroblasts
✍ Scribed by Marikki Laiho; Olli Saksela; Jorma Keski-Oja
- Book ID
- 115892009
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 936 KB
- Volume
- 164
- Category
- Article
- ISSN
- 0014-4827
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## Abstract ## Objective To investigate the molecular mechanism of the overexpression of transforming growth factor β receptors (TGFβRs) in dermal fibroblasts from patients with systemic sclerosis (SSc). ## Methods Dermal fibroblasts from 7 patients with diffuse SSc of recent onset and from 7 he
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