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Transforming growth factor-β 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition

✍ Scribed by Xu, Hui-Mian


Book ID
120187446
Publisher
Spandidos Publications Ltd
Year
2012
Tongue
English
Weight
698 KB
Volume
29
Category
Article
ISSN
1021-335X

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Transforming growth factor-β1 enhances t
✍ Antonietta R. Farina; Anna Coppa; Antonella Tiberio; Antonella Tacconelli; Aless 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 201 KB 👁 1 views

Transforming growth factor-beta (TGF␤1) enhances human MDA-MB-231 breast tumour cell invasion of reconstituted basement membrane in vitro but does not inhibit proliferation of this cell line. In contrast to basal invasion, which is plasmin-, urokinase (uPA)-, tissue-type plasminogen activator (t-PA)