Transforming Growth Factor-α and Rhinitis
✍ Scribed by Samuel M. Lam; De-Fen Zhu; Jeffrey M. Ahn
- Book ID
- 110082020
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 798 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0023-852X
No coin nor oath required. For personal study only.
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Two types of growth factors have been termed transforming growth factors (TGFs). One of these, TGF-a, is related to epidermal growth factor (EGF) and binds to the EGF receptor, while the other one, TGF-P, is a structurally unrelated protein with a distinct receptor. The initial observation that led
Transforming growth factor-a and hepatocyte growth factor are important stimulators of hepatocyte proliferation. In this series of experiments we sought to measure the expression of transforming growth factor-a mRNA by hepatocytes in response to toxic liver injury produced by carbon tetrachloride or
## BACKGROUND. Transforming growth factor-␣ (TGF-␣) is a potent stimulator of cell proliferation in the liver and in liver tumors; however, its significance and association with hepatocyte proliferation remains unclear. ## METHODS. Expression of TGF-␣ and proliferation markers, such as prolifer