Leukocyte transmigration across the blood-brain barrier (BBB) is a cardinal feature of central nervous system (CNS) inflammation. Astrocytes form an integral part, both structurally and functionally, of the BBB. Vascular cell adhesion molecule-1 (VCAM-1), a member of the immunoglobulin gene superfam
Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of neural cell adhesion molecule in human hepatocellular carcinoma
✍ Scribed by Balzarini, Piera; Benetti, Anna; Invernici, Gloria; Cristini, Silvia; Zicari, Sonia; Caruso, Arnaldo; Gatta, Luisa B; Berenzi, Angiola; Imberti, Luisa; Zanotti, Cinzia; Portolani, Nazario; Giulini, Stefano M; Ferrari, Maura; Ciusani, Emilio; Navone, Stefania E; Canazza, Alessandra; Parati, Eugenio A; Alessandri, Giulio
- Book ID
- 111907510
- Publisher
- Nature Publishing Group
- Year
- 2012
- Tongue
- English
- Weight
- 626 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0023-6837
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## Abstract Transforming growth factor‐beta (TGF‐beta) plays a dual and complex role in human cancer. In this report, we observe a specific set of MicroRNAs (miRNAs) changed in response to TGF‐beta in human hepatocellular carcinoma (HCC) cells by miRNA microarray screening. A cluster of miRNA, miR‐